Velazquez Lab of Neurodegenerative Diseases - VLoND

Current Funding

  1. T32 NIH (MPI Wu, Velazquez, Li, Klein-Seetharaman) (2024-2029)
    PI on a training grant, immersing PhD students to Alzheimer’s disease via artificial intelligence, clinical immersion, and neurobiology.
  2. ASU Edson Seed Grant (PI Velazquez) (2024-2025)
    PI on a seed grant to develop a new Microglial Dyrk1a conditional knockout mouse to understand mechanism tied to inflammation and cytokine release.
  3. R01 AG062500 HHS: NIH (PI Velazquez) (2019-2024)
    PI on a grant to identify how the ribosomal protein S6 kinase beta-1 (S6K1) mechanistically links aging and AD.
  4. R01 AG059627 HHS: (NIH PI Velazquez) (2019-2023)
    PI on a grant to identify common mechanisms of neurodegeneration between Down syndrome (DS) and AD.

Completed Funding

  1. R42NS129400-01 Small Business Technology Transfer
    (STTR) HHS, NINDS: (PI Dunckley, Hulme; Collaborator Velazquez) (2022-2024)
    Collaborator for two years on commercialization of selective Dyrk1a inhibitors for Down Syndrome.
  2. Developmental Research grant (NIH-Arizona Alzheimer's Consortium); PI Velazquez; Co-PI Huentelman TGen; CO-PI Karr, ASU), (2021-2023)
    PI on a 2-year grant to investigate the role of Neuronal Rbbp7 as a mediator against tau pathology in Alzheimer’s disease and related tauopathies.
  3. Edson Foundation Seed grant (ASU Foundation; PI Dunckley, Co-PI Velazquez), (2021-2022)
    Co-PI on a 1-year grant to test a novel Dyrk1a inhibitor in the 3xTg-AD mouse model of AD.
  4. Edson Foundation Seed grant (ASU Foundation; PI Mastroeni, Co-PI Velazquez), (2021-2022)
    Co-PI on a 1-year grant to test whether dysfunctional neuronal mitochondria translocate into neighboring glial cells via tunneling nanotubes.
  5. Edson Foundation Seed grant (ASU Foundation; PI Velazquez; Collaborators TGen; Huentelman and Pirrotte), (2020-2022)
    PI on a 2-year grant to determine if glyphosate exposure is associated with cognitive aging and Alzheimer’s Disease (AD).
  6. IDSA - The Role of Microbe-induced Necroptotic Death in Tauopathy (PI Jacobs; Co-PI Velazquez), (2020-2021)
    Co-PI on a grant to determine mechanisms of cell death in Alzheimer’s disease and related tauopathies.
  7. Alzheimer’s Association International Research Grant (PI Velazquez), (2016-2020)
    PI on a 3-year grant to investigate Pim1 inhibition as a novel target for AD leveraging a nanoparticle technology.
  8. P30 AG019610: Pilot grant (PI Velazquez), (2019-2020)
    PI on a 1-year grant to collect preliminary data on the Pim1 kinases’ involvement in AD.
  9. National Science Foundation Post-Doctoral Research Fellowship, (PI Velazquez), (2016-2018)
    PI on a 2-year grant to elucidate the underlying molecular mechanisms linked to choline supplementation and healthy cognitive aging.
  10. National Science Foundation Graduate Research Fellowship (2009-2012)
    Graduate funding to examine the neural mechanisms associated with maternal choline supplementation cognitive benefits.
  11. Cornell University Sage Graduate Fellowship (2008-2010)
    Two-year graduate funding plus 4 summers awarded to top incoming graduate students.